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18248 : Reduced ?-catenin Expression in Mouse Cardiomyocytes Increases Matrix Metalloproteinase Activation and Apoptosis, Producing Greater Post-Infarction Ventricular Dysfunction

Researchers

Presenter

  • Anton Mihic

Principal Investigators

  • Kota Hatta

  • Saeid Amini-Nik

  • Jun Wu

  • Shu-hong Li

  • Lu Sun

  • Benjamin A Alman

  • Keith R Brunt

  • Richard D Weisel

  • Ren-Ke Li

Medical Centers

  • The Hosp for Sick Children and Res Inst, Toronto, ON, Canada

  • Toronto General Hospital/Research Institute (UHN), Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Myocardial infarction

  • Congestive heart failure

Biomarkers

  • Matrix metalloproteinase

  • TIMP Metallopeptidase Inhibitor 3

Drug/Treatment

  • TIMP-3 secretion inducer

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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