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16253 : Cyclosporine-a Mediated Impairment of Human Coronary Artery Smooth Muscle Cell Phospho-nrf2 and Vascular Injury Function Are Rescued by Tert-Butylhydroquinone

Researchers

Presenter

  • Mitesh V Badiwala

Principal Investigators

  • Laura C Tumiati

  • Liza Grosman-Rimon

  • Phyllis Billia

  • Scott Heximer

  • Matthew T Da Silva

  • Thomas F Lindsay

  • Stephan S Bolz

  • Vivek Rao

Medical Centers

  • Toronto Western Hospital, Toronto, ON, Canada

  • U Toronto, Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Cardiac allograft vasculopathy

  • Vasospasm

Biomarkers

  • Endothelin-1

Drug/Treatment

  • Nitroprusside sodium

  • Cyclosporine A

  • Acetylcholine

  • Phenylephrine

  • Cyclosporine eent

  • endothelin-1

  • Nitric oxide

  • DMSO

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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