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13228 : Nuclear AT1/AT2 Receptors Mediate Intracrine Angiotensin II Induced Fibrosis-related Gene Expression Changes in Atrial Fibroblasts

Researchers

Presenter

  • George Vaniotis

Principal Investigators

  • Clemence Merlen

  • Danny Del Duca

  • Terence E. Hebert

  • Bruce G. Allen

  • Stanley Nattel

Medical Centers

  • Univ de Montreal and Montreal Heart Inst, Montreal, QC, Canada

  • McGill, Montreal, QC, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Arrhythmia

Biomarkers

  • Nitric oxide

  • Platelet derived growth factor

  • Endothelial cell nitric oxide synthase

  • Lamin A/C

  • Solute Carrier Family 33 Member 1

Drug/Treatment

  • Angiotensin II

  • Nitric oxide

  • Lorestan

  • Prezatide copper acetate

  • Becaplermin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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