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13175 : Impaired Activity of The Thioredoxin Reducing System Contributes to Diabetic Cardiac Disease: Evidence from Human and Experimental Studies

Researchers

Presenter

  • Richard E Gilbert

Principal Investigators

  • kabir Golam

  • Yanling Zhang

  • Suzanne L Advani

  • Kim A Connelly Esq

Medical Centers

  • Canada., St. Michaels Hosp and Univ of Toronto, Keenan Res Ctr in the Li Ka Shing Knowledge Inst, Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Diabetic cardiomyopathy

  • Hypertrophic cardiomyopathy

  • Heart muscle disease

  • Congestive heart failure

  • Diabetes

Biomarkers

  • 3-nitrotyrosine

  • Proto-oncogene tyrosine-protein kinase ROS

  • Thioredoxin

Drug/Treatment

  • Streptozotocin

  • thioredoxin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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