// App-Quantinova.ai

13073 : Adiponectin Protects Against Autoimmune Myocarditis by Inhibiting Toll-Like Receptor 4 Mediated Cardiac Inflammation And Injury

Researchers

Presenter

  • Sabrina Wilk

Principal Investigators

  • Madlen Lobel

  • Urs Eriksson

  • Alan Valaperti

  • Peter Liu

  • Heinz-Peter Schultheiss

  • Carmen Scheibenbogen

  • Carsten Skurk

Medical Centers

  • Charite Univsmedizin Berlin, Berlin, Germany

  • Toronto General Hospital, University of Toronto, Toronto, ON, Canada

  • Univ Hosp, Zurich, Switzerland

Locations

  • Germany

  • Switzerland

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Autoimmune Myocarditis

Biomarkers

  • Adiponectin

  • Dual specificity mitogen-activated protein kinase kinase 1

  • C-C Motif Chemokine Ligand 2

  • Myeloid differentiation factor 88

  • Cluster of Differentiation 14

  • Cluster of Differentiation 19

  • Cluster of Differentiation 2AP

  • Cluster of differentiation 45

  • Cyclic AMP-dependent protein kinase

  • Cyclooxygenase-2

  • Intercellular adhesion molecule 1

  • Interleukin 12

  • Interleukin 6

  • Toll like receptor 4

  • Tumor necrosis factor

Drug/Treatment

  • ICAM-1

  • IL-12

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim