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11582 : Angiotensin 1-7 Ameliorates Diabetic Cardiomyopathy in db/db Mice by Reducing Lipotoxicity: A Critical Role for Adipose Triglyceride Lipase

Researchers

Presenter

  • Vaibhav B Patel

Principal Investigators

  • Osama Abo Alrob

  • Ratnadeep Basu

  • Tariq Altamimi

  • Alexander Choy

  • Cory S Wagg

  • Zamaneh Kassiri

  • Gary D Lopaschuk

  • Gavin Y Oudit

Medical Centers

  • Univ. of Alberta, Edmonton, Alberta, Canada.

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Diabetic cardiomyopathy

  • Diastolic dysfunction

  • Cardiac fibrosis

  • Heart muscle disease

  • Obesity

Biomarkers

  • Forkhead Box O1

  • Human albumin

  • Triglyceride Level

  • Sirtuin 1

Drug/Treatment

  • Angiotensin II

  • Palmitic acid

  • lipase

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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