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10886 : Targeting Endoglin Activity Improves Survival and Reduces Right Ventricular Fibrosis in a Murine Model of Pulmonary Arterial Hypertension

Researchers

Presenter

  • Xiaoying Qiao

Principal Investigators

  • Emily E Mackey

  • Vikram Paruchuri

  • Gerard H Daly

  • Prerna Nepali

  • Mark J Aronovitz

  • Michelle Letarte

  • Richard H Karas

Medical Centers

  • U Toronto, Toronto, ON, Canada

  • Tufts Medical Center, Boston, MA

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Central Nervous System (CNS)

Disease

  • Pulmonary arterial hypertension

  • Congestive heart failure

  • Hypertension

  • Stroke

Biomarkers

  • Extracellular signal-regulated kinase

Drug/Treatment

  • TRC105

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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