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15414 2014 AHA : Ablation of Aryl Hydrocarbon Nuclear Translocator (ARNT) in the Heart Leads to Diabetic Cardiomyopathy Phenotype Through PPAR? Activity

Researchers

Presenter

  • Hsiang Chun Chang

Principal Investigators

  • Minh Tran

  • Hossein Ardehali

  • Kusum Chawla

  • Arineh Khechaduri

  • Xiaomeng Chai

  • Mohsen Ghanefar

  • Marina Bayeva

  • Cory Wagg

  • Frank Gonzalez

  • Gary Lopaschuk

Medical Centers

  • Mazankowski Alberta Heart Institute, Edmonton, AB, Canada

  • Feinberg Cardiovascular Research Institute, Chicago, IL

  • Ctr for Cancer Res Natl Cancer Inst, Bethesda, MD

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Diabetic cardiomyopathy

  • Dilated cardiomyopathy

  • Congestive heart failure

  • Heart muscle disease

  • Diabetes

Biomarkers

  • Peroxisome proliferator activated receptor

  • HIF 1 beta

  • Hypoxia-inducible factor-1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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