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14628 2014 BOS : Elucidation of the Mechanism of Apolipoprotein(a)/Lipoprotein(a)-Induced Interleukin 8 Gene Expression: Insight into Potential Receptors and Signaling Pathways and the Role of Oxidized Phospholipids

Researchers

Presenter

  • Sera Sayegh

Principal Investigators

  • Michael B Boffa

  • Marlys L Koschinsky

Medical Centers

  • University of Windsor, Windsor, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Coronary Artery Disease

Biomarkers

  • Mitogen-activated protein kinase

  • Mitogen-activated protein kinase 3

  • c-Jun N-terminal kinase

  • Interleukin-8

  • JunB proto-oncogene, AP-1 transcription factor subunit

  • Toll like receptor 4

  • Toll-like receptor 2

Drug/Treatment

  • Interleukin

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim