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429 2014 HTN : PTP1B, a Link Between Endoplasmic Reticulum Stress and Endothelial Dysfunction

Researchers

Presenter

  • Ruchi Anderson

Principal Investigators

  • Joseph B Norman

  • Michel L Tremblay

  • Anne-Cecile E Huby

  • Vijay S Patel

Medical Centers

  • Georgia Regents University, August, GA

  • McGill Rosalind and Morris Goodman Cancer Res Ctr, Montreal, QC, Canada

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Vasodilation dysfunction

  • Diabetes

Biomarkers

  • Nucleoside diphosphate kinase A

  • Protein tyrosine phosphatase 1B

  • Proto-oncogene tyrosine-protein kinase ROS

  • DNA Damage Inducible Transcript 3

  • X-Box Binding Protein 1

Drug/Treatment

  • Thapsigargin

  • Tunicamycin

  • L-Tyrosine

  • Tempol

  • DMSO

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim