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366 2014 ATVB : Inhibition of Interleukin-1? by a Monoclonal Antibody Therapy Reduces Vascular Calcification in Ldlr-/- Mice

Researchers

Presenter

  • Maxime Denis

Principal Investigators

  • Anna Roubtsova

  • Hermann Gram

  • Nabil G Seidah

  • Jacques Genest

Medical Centers

  • McGill Univ, Westmount, QC, Canada

  • McGill, Montreal, QC, Canada

  • Institut de Recherches Cliniques de Montreal, Quebec, Canada.

Locations

  • Canada

Companies

  • Novartis AG

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Calcified vascular disease

  • Aortic valve calcification

  • Coronary Artery Disease

Biomarkers

  • Proprotein convertase subtilisin/kexin type 9

  • Interleukin 1

Drug/Treatment

  • Interleukin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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