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119 2014 ATVB : Nebivolol Suppresses Hypoxic-Induced Rat Thoracic Aortic Smooth Muscle Cell Apoptosis by a Mechanism Involving Nitric Oxide Production, HSP70 Upregulation and Inhibition of P53 Phosphorylation

Researchers

Presenter

  • Ioannis K Rizos

Principal Investigators

  • Ioannis K Toumpoulis

  • Vasileos Salpeas

  • Shehla Izhar

  • Thomas G Parker

Medical Centers

  • Keenan Res Ctr for Biomedical Science and Li Ka Shing Knowledge Inst of St. Michaels Hosp, Toronto, ON, Canada

  • Attikon University Hospital, Athens, Greece.

Locations

  • Canada

  • Greece

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Aneurysm of the ascending aorta

Biomarkers

  • 70 kilodalton heat shock proteins

  • p53

Drug/Treatment

  • Ascorbic acid

  • Nitric oxide

  • Nebivolol

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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