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ATVB04 2015 BOS : Mechanistic Studies of HDL Mimetic Peptide ATI-5261 Reveal Aspects of Class A Alpha-helix Structure that Induce Cytotoxicity and Hypertriglyceridemia in vivo: Design of Safe Analogs With Potent Anti-atherosclerosis and Anti-diabetic Actions

Researchers

Presenter

  • Vasanthy Narayanaswami

Principal Investigators

  • Greg Hura

  • Stefanie Bittner

  • Juveria Tabassum

  • Anouar Hafiane

  • Jacques Genest

  • Jan Johansson

  • Salman Azhar

Medical Centers

  • Artery Therapeutics, San Ramon, CA

  • Medicine, VA Palo Alto HealthCare System and Stanford University, Palo Alto, CA

  • California State Univ, Long Beach, CA

  • McGill Univ Health Ctr/Royal Victoria Hosp, Montgreal, QC

  • Lawrence Berkeley National Lab, Berkeley, CA

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Dyslipidemia

  • Coronary Artery Disease

  • Diabetes

Biomarkers

  • Alanine transaminase

  • Aspartate aminotransferase

  • Hemoglobin A1c

Drug/Treatment

  • Arginine hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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