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T1152 2015 AHA : Granzyme B Deficiency Protects Against Angiotensin II-induced Cardiac Fibrosis via a Perforin-independent Mechanism

Researchers

Presenter

  • Fang Cheng

Principal Investigators

  • Mehul Sharma

  • Lisa S Ang

  • Sarah J Williams

  • R Chris Bleackley

  • John E Eriksson

  • Michael A Seidman

  • Bruce M McManus

  • David J Granville

  • Yulia Merkulova

  • Sheetal A Raithatha

  • Leigh G Parkinson

  • Hongyan Zhao

  • Kathryn Westendorf

  • Lubos Bohunek

  • Tatjana Bozin

  • Ivy Hsu

Medical Centers

  • Univ of British Columbia, Turku, Finland

  • Abo Akademi Univ and Turku Ctr for Biotechnology, Turku, Finland

  • Univ. of Alberta, Edmonton, Alberta, Canada.

  • The University of British Columbia, Vancouver, BC, Canada

Locations

  • Finland

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Congestive heart failure

  • Cardiac fibrosis

Biomarkers

  • Granzyme B

Drug/Treatment

  • Angiotensin II

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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