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P601 2015 HTN : Matrix Metalloproteinase 2 Plays An Important Role In Angiotensin Ii-induced Vascular Injury Mediated In Part Through Epidermal Growth Factor Receptor Activation In Vascular Smooth Muscle Cells

Researchers

Presenter

  • Muhammad Oneeb Rehman Mian

Principal Investigators

  • Julio C. Fraulob-Aquino

  • Asia Rehman

  • Nourredine Idris-Khodja

  • Pierre Paradis

  • Ernesto L. Schiffrin

Medical Centers

  • Lady Davis Inst. for Med. Rsch., Montreal, QC, Canada

  • Sir Mortimer B. Davis-Jewish General Hospital, Montreal, QC, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Hypertension

Biomarkers

  • C-C Motif Chemokine Ligand 2

  • Monocyte chemoattractant protein 1

  • Cluster of Differentiation 4

  • Cluster of differentiation 69

  • Cluster of differentiation 8A

  • Proto-oncogene tyrosine-protein kinase ROS

  • Epidermal growth factor receptor

  • Matrix metalloproteinase

  • Vascular cell adhesion molecule 1

Drug/Treatment

  • Angiotensin II

  • Acetylcholine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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