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P062 2015 HTN : Long-term Exposure to Endothelin-1 Overexpression Increases Blood Pressure and Causes Small Artery Injury

Researchers

Presenter

  • Sofiane Ouerd

Principal Investigators

  • Julio C. Fraulob-Aquino

  • Stefan Offermanns

  • Pierre Paradis

  • Ernesto L. Schiffrin

Medical Centers

  • Lady Davis Inst. for Med. Rsch., Montreal, QC, Canada

  • Max-Planck-Inst for Heart and Lung Res, and J.W. Goethe Univ Frankfurt, Bad Nauheim, Germany

  • Lady Davis Inst for Medical Res and McGill Univ, Montreal, QC, Canada

Locations

  • Canada

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Nephrology

Disease

  • Acute renal failure

Biomarkers

  • Endothelin-1

Drug/Treatment

  • Nitroprusside sodium

  • Acetylcholine

  • endothelin-1

  • Tamoxifen

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim