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S5146 2016 AHA : Enhanced Receptor-independent Nucleoside Diphosphate Kinase Mediated Gs Protein Signaling Contributes to Arrhythmogenic Calcium Mishandling in Atrial Fibrillation

Researchers

Presenter

  • Issam Abu-Taha

Principal Investigators

  • Patrice Naud

  • Xiao Yan Qi

  • Vanessa Gundlach

  • Markus Kamler

  • Thomas Wieland

  • Stanley Nattel

  • Dobromir Dobrev

Medical Centers

  • Univ de Montreal and Montreal Heart Inst, Montreal, QC, Canada

  • University of Duisburg-Essen, Essen, Germany

  • Inst of Pharmacology, Univ of Duisburg-Essen, Essen, Germany

  • University of Heidelberg, Mannheim, Germany

Locations

  • Canada

  • Germany

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Arrhythmia

  • Coronary Artery Disease

Biomarkers

  • Ataxia Telangiectasia And Rad3-Related Protein

  • Nucleoside diphosphate kinase A

  • Cyclic adenosine monophosphate

  • Ryanodine receptor type 2

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim