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P224 2016 HTN : Endothelin-1 Overexpression Preserves Endothelial Function in Mice with Vascular Smooth Muscle Cell-specific Deletion of PPAR-gamma

Researchers

Presenter

  • Noureddine Idris-Khodja

Principal Investigators

  • Michelle Trindade

  • Jordan Gornitsky

  • Asia Rehman

  • Tlili Barhoumi

  • Stefan Offermanns

  • Frank J. Gonzalez

  • Mario F. Neves

  • Pierre Paradis

  • Ernesto L. Schiffrin

Medical Centers

  • McGill Univ, Sir Mortimer B. Davis-Jewish General Hosp, Lady Davis Inst for Medical Res and Dept of Med, Vascular and Hypertension Res Unit, Montreal, QC, Canada

  • Natl Cancer Inst, Natl Insts of Health, Bethesda, MD

  • Max Planck Institute for Heart and Lung Research, Bad Nauheim, Germany.

  • McGill Univ, Sir Mortimer B. Davis-Jewish General Hosp, Lady Davis Inst for Medical Res and Dept of Med, Vascular and Hypertension Res Unit, Montreal, QC, Canada

  • Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

Locations

  • United States

  • Canada

  • Germany

  • Brazil

Companies

  • N/A

Study Components

Therapeutic Area

  • Angiology

Disease

  • Vasodilation dysfunction

  • Calcified vascular disease

Biomarkers

  • Endothelin-1

Drug/Treatment

  • Angiotensin II

  • Acetylcholine

  • endothelin-1

  • Tamoxifen

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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