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88 2016 BCVS : Cardiac-specific Deletion of Protein Tyrosine Phosphatase 1B Exacerbates Pressure Overload-induced Hypertrophy and Heart Failure in Mice

Researchers

Presenter

  • Alexandre Bergeron

Principal Investigators

  • Yanfen Shi

  • David Labbe

  • Michel Tremblay

  • Gerard Karsenty

  • Benoit Boivin

Medical Centers

  • SUNY Polytechnic Institute, Albany, NY

  • Columbia University, New York, NY

  • McGill, Montreal, QC, Canada

  • Montreal Heart Institute, Montreal, Quebec, Canada

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

Disease

  • Hypertrophic cardiomyopathy

  • Congestive heart failure

Biomarkers

  • Nucleoside diphosphate kinase A

  • Protein tyrosine phosphatase 1B

  • Proto-oncogene tyrosine-protein kinase ROS

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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