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1470 : TYK2-STAT1 Pathway Positively Regulates BCL2 Gene Expression in T-Cell Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Jeffrey W Tyner

Principal Investigators

  • Jessica Tatarek

  • Angela G. Fleischman

  • Yebin Ahn

  • Yandan Yang

  • Wenjun Zhou

  • Donna S. Neuberg

  • Richard Moriggl

  • Alejandro Gutierrez

  • Mathias Muller

  • Michelle Kelliher

  • Catriona Jamieson

  • Nathanael S Gray

  • Louis M. Staudt

  • Brian J. Druker

  • Thomas Look

  • Vu N Ngo

  • Jason M Glover

  • Bill H Chang

  • Arla J Yost

  • Andrew P Weng

Medical Centers

  • Department of Biostatistics & Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

  • Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria

  • Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Vienna, Austria

  • Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Locations

  • Canada

  • Austria

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • B-cell lymphoma 2

  • Janus kinase

Drug/Treatment

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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