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1266 : Outcome and Clinical Characteristics of Clonal and Malignant Myeloid Transformation in Inherited Bone Marrow Failure Syndromes

Researchers

Presenter

  • Catherine I. Segbefia

Principal Investigators

  • Sharon Abish

  • MacGregor Steele

  • Kaiser Ali

  • Nancy Dower

  • Uma Athale

  • Lawrence Jardine

  • Lisa Goodyear

  • Isaac Odame

  • Patricia Canning

  • Bozana Zlateska

  • Conrad V Fernandez

  • Lillian Sung

  • Joseph Beyene

  • Yigal Dror

  • Rochelle Yanofsky

  • John K. Wu

  • Josette Champagne

  • Mariana Silva

  • Jeffrey H. Lipton

  • Josee Brossard

  • Yvan Samson

Medical Centers

  • Pediatric Oncology, Alberta Childrens Hospital, Calgary, AB, Canada

  • paediatric rheumatology, sickkids hospital, Toronto, ON, Canada

  • Princess Margaret Hospital, Toronto, ON, Canada

  • Department of Paediatrics, Division of Emergency Medicine, The Hospital for Sick Children, Toronto, ON, Canada

  • Paediatric Haematology/Oncology, MUHC-Montreal Children's Hospital, Montreal, QC, Canada

  • Paediatric Haematology/Oncology, Kingston General Hospital, Kingston, ON, Canada

  • IWK Health Center, Dalhousie University, Halifax, NS, Canada

  • Paediatric Haematology/Oncology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada

  • Pediatrics, Div. Hem./Onc, Children's Hosp. of Eastern Ontario, Ottawa, ON, Canada

  • Paediatric Haematology/Oncology, Children's Hospital of Western Ontario, London, ON, Canada

  • Division of Pediatric Hematology/ Oncology, McMaster University, Hamilton, Canada

  • Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, Canada

  • paediatric rheumatology, sickkids hospital, Toronto, ON, Canada

  • Paediatric Haematology/Oncology, Aberhart Centre One, Edmonton, AB, Canada,

  • Pediatrics, BC Womenss and Childrens Hospital, Vancouver, BC, Canada

  • Paediatric Haematology/Oncology, Hopital Ste-Justine, Montreal, QC, Canada

  • Paediatric Haematology/Oncology, University of Manitoba, CancerCare Manitoba, Winnipeg, MB, Canada

  • Paediatric Haematology/Oncology, Centre Hospitalier Universitaire de Sherbrooke, Sherbrooke, QC, Canada

  • Department of Paediatrics, Division of Emergency Medicine, The Hospital for Sick Children, Toronto, ON, Canada

  • Paediatric Haematology/Oncology, Janeway Child Health Centre, St. John's, NF, Canada

  • Pediatric Rheumatology, University of Saskatchewan, Saskatoon, SK, Canada

  • paediatric rheumatology, sickkids hospital, Toronto, ON, Canada

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Shwachman-diamond syndrome

  • Alpha-thalassemia myelodysplasia syndrome

  • Acute myelocytic leukemia

  • Fanconi anemia

  • Anemia

Biomarkers

  • Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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