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2937 : Small Molecule MIRA-1 Induces p53-Independent Apoptosis in Multiple Myeloma Cells Through Activation of the p38 MAPK Signaling Pathway.

Researchers

Presenter

  • Hua Jiang

Principal Investigators

  • Yijun Yang

  • Donna Reece

  • Hong Chang

Medical Centers

  • Laboratory Hematogy and Medical Oncology, University Health Network, Toronto, ON, Canada

  • Laboratory Genetics, University Health Network, Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Multiple Myeloma

  • Solid malignancies

Biomarkers

  • Mitogen-activated protein kinase

  • Myeloid Cell Leukemia 1

  • p38 Mitogen-activated protein kinases

  • Early Growth Response 1

  • Translocator protein

  • MAPK Interacting Serine/Threonine Kinase 1

Drug/Treatment

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Doxorubicin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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