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2772 : The RNA Editase ADAR1 Promotes Malignant Progenitor Reprogramming in Chronic Myeloid Leukemia.

Researchers

Presenter

  • Leslie Crews-Robertson

Principal Investigators

  • Christian L Barrett

  • Lawrence S. B. Goldstein

  • Marco A. Marra

  • Kelly A Frazer

  • Catriona Jamieson

  • Hyn-June Chun

  • Angela C. Court-Recart

  • Daniel J Goff

  • Mark D. Minden

  • Anil Sadarangani

  • Jessica Rusert

  • Kim-Hien Dao

  • Sheldon R Morris

Medical Centers

  • Department of Surgery, University of California San Diego, San Diego, CA

  • Genome Sciences Centre, BC Cancer Agency, Vancouver, BC, Canada

  • Division of Medical Oncology, Princess Margaret Hospital/University of Toronto, Toronto, ON, Canada

  • Canada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada

  • Moores Cancer Center, University of California, San Diego, La Jolla, CA

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Chronic Myelogenous Leukemia

Biomarkers

  • Abelson murine leukemia viral oncogene homolog 1

  • Adenosine deaminase RNA specific

  • Breakpoint Cluster Region

Drug/Treatment

  • Interferon

  • Adenosine

  • Adenosine Intravenous

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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