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2624 : Glutaminase Inhibition Selectively Slows the Growth of Primary Acute Myeloid Leukemia (AML) Cells with Isocitrate Dehydrogenase (IDH) Mutations.

Researchers

Presenter

  • Sung Ah Jun

Principal Investigators

  • Takashi Tsukamoto

  • Amir T Fathi

  • Mark D. Minden

  • Chi Van Dang

Medical Centers

  • Institute of Medical Sciences, University of Toronto, Toronto, ON, Canada

  • Department of Medical Oncology and Hematology, Princess Margaret Hospital, University of Toronto, Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

Disease

  • Myeloid neoplasms

  • Myelodysplastic Syndrome

  • Acute myelocytic leukemia

  • Tuberculosis

Biomarkers

  • Isocitrate dehydrogenase 1

  • Isocitrate dehydrogenase 2

Drug/Treatment

  • Glutamine

  • DMSO

Outcome

  • N/A

Study Design

  • double blind/blinded

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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