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2581 : AML Cells Have Altered Mitochondrial Biogenesis and Low Spare Reserve Capacity in Their Respiratory Chain That Renders Them Susceptible to Oxidative Metabolic Stress.

Researchers

Presenter

  • Timothy E Chung

Principal Investigators

  • Marko Skrtic

  • Rob C. Laister

  • Peter Mullen

  • Stephanie Xie

  • Linda Penn

  • Ian M. Rogers

  • John E. Dick

  • Mark D. Minden

  • Aaron D Schimmer

  • Bozhena Jhas

  • Rose Hurren

  • Marcela Gronda

  • Xiao Ming Wang

  • Yulia Jitkova

  • Mahadeo A. Sukhai

  • Feng-Hsu Lin

  • Neil Maclean

Medical Centers

  • Princess Margaret Hospital, Toronto, ON, Canada

  • Ontario Cancer Institute, Toronto, ON, Canada

  • Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

  • The Campbell Family Institute for Cancer Research and Ontario Cancer Institute, Toronto, ON, Canada

  • Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Infectious Diseases (ID)

Disease

  • Tuberculosis

Biomarkers

  • Cluster of Differentiation 34

  • Eukaryotic translation elongation factor 1 alpha 1

Drug/Treatment

  • Palmitic acid

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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