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2341 : Short Term Signalling Responses of the Most Primitive Subsets of Human Hematopoietic Cells Stimulated in Vitro Correlate with Their Subsequent Self-Renewal Behaviour.

Researchers

Presenter

  • Sean C. Bendall

Principal Investigators

  • Sang-Hoon

  • Connie J. Eaves

  • Paul H. Miller

  • Alice M.S. Cheung

  • Suzan Imren

  • R. Keith Humphries

  • Ryan R. Brinkman

  • Robert A.J. Oostendorp

  • Garry P. Nolan

Medical Centers

  • Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

  • III. Department of Internal Medicine, Hematology/Oncology, Technical University of Munich, Munich, Germany

Locations

  • Canada

  • Germany

Companies

  • Baxter International

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Mitogen-activated protein kinase 3

  • Phosphorylated mitogen-activated protein kinase 3

  • Phosphorylated signal transducer and activator of transcription 3

  • Phosphorylated signal transducer and activator of transcription 5

  • Phosphorylated-AKT

  • Cluster of Differentiation 34

  • Cluster of Differentiation 38

  • Proliferation marker protein Ki-67

  • CREB-binding protein

  • Granulocyte colony-stimulating factor

  • Interleukin 6

  • Signal transducer and activator of transcription 3

  • Signal transducer and activator of transcription 5

  • Spleen tyrosine kinase

  • Thy-1 Cell Surface Antigen

Drug/Treatment

  • Filgrastim

  • ZAP70

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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