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1025 : Innate Immune Cell Expression of Pattern Recognition Receptors From ?-Thalassemia Patients During Intensive Combination Chelation Therapy

Researchers

Presenter

  • Patrick BWalter

Principal Investigators

  • Paul Harmatz

  • John B. Porter

  • Nancy Sweeters

  • Jackson Price

  • Alisha Manji

  • David Killilea

  • Ashutosh Lal

  • Elliott Vichinsky

  • Annie Higa

  • Vivian Ng

  • Marcela G Weyhmiller

  • Patricia Evans

Medical Centers

  • Gastroenterology, St Georges Hospital University of London, London, United Kingdom

  • University of Victoria, Victoria, BC, Canada

Locations

  • Canada

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Blood/haematological Diseases

Disease

  • Beta-thalassemia

  • Hemochromatosis

  • Thalassemia

Biomarkers

  • ATPase H+ Transporting Accessory Protein 2

  • Peripheral blood mononuclear cell

  • Cluster of Differentiation 14

  • Progesterone receptor

  • Toll like receptor 4

  • Red Blood Cells

Drug/Treatment

  • Deferoxamine

  • Deferasirox

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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