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1076 : Comparative Cellular Studies of the VWF Exon 45 Deletion Mutation Using Patient-Derived Blood Outgrowth Endothelial Cells (BOEC) and Megakaryocytes

Researchers

Presenter

  • Mackenzie L Bowman

Principal Investigators

  • Ling Li

  • Fred Pluthero

  • Hilary Christensen

  • Irwin Walker

  • Walter Kahr

  • Paula D James

Medical Centers

  • Department of Oncology, Queens University, Kingston, ON, Canada

  • Departments of Paediatrics and Biochemistry, University of Toronto, The Hospital for Sick Children, Toronto, ON, Canada,

  • Program in Cell Biology, Hospital for Sick Children, Toronto, ON, Canada

  • Department of Biomedical and Molecular Sciences, Queen's University, Kingston, Ontario, Canada

  • McMaster University, Hamilton, ON, Canada

  • Division of Haematology/Oncology, Program in Cell Biology, The Hospital for Sick Children, Toronto, ON, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Cluster of Differentiation 34

  • von Willebrand factor

Drug/Treatment

  • Desmopressin

  • FVIII

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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