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1279 : Collaboration Between RUNX and NOTCH Pathways in T-Cell Acute Lymphoblastic Leukemia

Researchers

Presenter

  • Hongfang Wang

Principal Investigators

  • Olena O Shevchuk

  • Sonya H Lam

  • Vincenzo Giambra

  • Louis Wang

  • Samuel D Gusscott

  • Jon C Aster

  • Andrew P Weng

Medical Centers

  • Terry Fox Laboratory, BC Cancer Agency, Vancouver, BC, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • T-cell acute lymphoblastic leukemia

Biomarkers

  • Neurogenic locus notch homolog protein 1

  • ETV6-RUNX1

  • Insulin-like growth factor 1 receptor

  • Runt Related Transcription Factor 3

  • Trimethylation of lysine 27 on histone H3

Drug/Treatment

  • Navitoclax

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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