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1944 : Higher Proportions of IFNg-Producing T Cells, CD56bright NK Cells and Immature B Cells in the Lymphocytes of G-CSF Stimulated Donor Grafts Are Associated with Less Chronic Gvhd After HSCT: Results From the Canadian BMT Group 0601 Randomized, Phase III Trial

Researchers

Presenter

  • Aminia Kariminia

Principal Investigators

  • Megan Levings

  • Gerald Devins

  • Holly Margaret Kerr

  • Stephanie J Lee

  • David Swajcer

  • Cynthia L. Toze

  • Stephen Couban

  • Kirk R. Schultz

  • Raewyn Broady

  • Tony Panzarella

  • Alisha Albert-Green

  • Mahmoud Aljurf

  • Hind Al Humaidan

  • Ronan Foley

Medical Centers

  • Vancouver General Hospital, Vancouver, BC, Canada

  • Riyadh, ., Saudi Arabia

  • Div. Pediatric Hem./Onc./ BMT, BC Childrens Hospital, Vancouver, BC, Canada

  • Internal Medicine, Leukemia/Bone Marrow Transplant Program, Division of Hematology, Vancouver, BC, Canada

  • Child and Family Research Institute, Vancouver, BC, Canada

  • Oncology Center, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia

  • King Faisal Specialist Hospital & CancerCare Manitoba, Winnipeg, MB, Canada

  • Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

  • Hamilton Health Sciences, Hamilton, ON, Canada

  • Sciences Centre, Queen Elizabeth II Health, Halifax, NS, Canada

  • Div. Pediatric Hem./Onc./ BMT, BC Childrens Hospital, Vancouver, BC, Canada

  • University of Toronto, Toronto, ON, Canada

  • Pediatric Hematology/Oncology/BMT, BC Childrens Hospital,

  • Department of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON, Canada

Locations

  • Canada

  • Saudi Arabia

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Hematological malignancies

  • Graft-versus-host disease

Biomarkers

  • Natural Killer cells

  • Peripheral blood mononuclear cell

  • Cluster of Differentiation 19

  • Cluster of Differentiation 2AP

  • Cluster of Differentiation 4

  • Granulocyte colony-stimulating factor

Drug/Treatment

  • Filgrastim

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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