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Su1945 : Hydrogen Sulfide (H2S)-Releasing Derivative of Naproxen Atb-346 Protects the Gastric Mucosa Compromised by Stress. a Comparative Study With Naproxen and Cyclooxygenase (COX)-2 Inhibitor

Researchers

Presenter

  • Katarzyna Jasnos

Principal Investigators

  • Danuta Drozdowicz

  • Agata Ptak-Belowska

  • Kyle L. Flannigan

  • Slawomir Kwiecien

  • John L. Wallace

  • Tomasz Brzozowski

Medical Centers

  • Jagiellonian University Medical College, Cracow, Poland

  • Medecine, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, Ontario, Canada

Locations

  • Poland

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • N/A

Disease

  • N/A

Biomarkers

  • Myeloperoxidase

  • Prostaglandin E2

  • Proto-oncogene tyrosine-protein kinase ROS

  • Cyclooxygenase-2

  • Interleukin 1

  • Malondialdehyde

  • Superoxide dismutase

  • Tumor necrosis factor

Drug/Treatment

  • Prostaglandin

  • glutathione

  • Celecoxib

  • ALT-210

  • Naproxen Sodium

  • ATB-346

  • Dinoprostone

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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