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Sa1178 : Evidence for Histamine-Mediated Sensitization of TRPV1 Signaling in Sensory Neurons in Mice and IBS Patients

Researchers

Presenter

  • Yeranddy A Alpizar

Principal Investigators

  • Yasmin Nasser

  • Eduardo E. Valdez-Morales

  • An Moonen

  • Carla Cirillo

  • Stephen J. Vanner

  • Karel Talavera

  • Pieter Vanden Berghe

  • Mira M. Wouters

  • Guy E. Boeckxstaens

Medical Centers

  • Gastrointestinal Diseases Research Unit, Dept of Medicine, Queens University, Kingston, Ontario, Canada

  • Laboratory of Ion Channel Research, KULeuven, Leuven, Belgium

Locations

  • Canada

  • Belgium

Companies

  • Translational Resear

Study Components

Therapeutic Area

  • Gastroenterology (GU)

Disease

  • Irritable Bowel Syndrome

Biomarkers

  • Sperm Acrosome Associated 9

Drug/Treatment

  • Mepramide

  • Capsaicin

  • NGX1998

  • histamine

  • Ebastine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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