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Tu1744 : the Relationship Between Common IBD-Associated Risk Alleles and Intestinal Permeability in a Cohort of Healthy First Degree Relatives of Individuals With Crohn's Disease

Researchers

Presenter

  • Karen Madsen

Principal Investigators

  • Charles N. Bernstein

  • Alain Bitton

  • Levinus A. Dieleman

  • David S. Guttman

  • Hien q. Huynh

  • Kevan Jacobson

  • Gilaad G. Kaplan

  • John K. Marshall

  • Remo Panaccione

  • Ernest G. Seidman

  • Wei Xu

  • Kathy Siminovitch

  • Denis Snider

  • Andrew Stadnyk

  • A. Hillary Steinhart

  • Michael Surette

  • Dan Turner

  • Bruce Vallance

  • Thomas D. Walters

  • Ken Croitoru

  • Konstantin Shestopaloff

  • Ummiye Venus Onay

  • Andrew D. Paterson

  • Anne M. Griffiths

  • Paul Moayyedi

  • Mark J. Ropeleski

  • Paul L. Beck

Medical Centers

  • Division of Hematology, University of British Columbia, Vancouver, BC, Canada

  • Crohn's & Colitis Foundation of Canada, Michael J Howorth GEM Project Team, Toronto, ON, Canada

  • Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada

  • Division of Urology, McMaster University, Hamilton, ON, Canada

  • Psychiatry, Dalhousie University, Halifax, NS, Canada

  • Zane Cohen Centre for Digestive Diseases, Mount Sinai Hospital, Division of Gastroenterology, Department of Medicine, University of Toronto, Toronto, ON, Canada

  • Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada

  • Division of Nephrology, University of Calgary, Calgary, AB, Canada

  • Department of Medicine, McMaster University, Hamilton, ON, Canada

  • Division of Hematology, University of Alberta, Edmonton, AB, Canada

  • Division of Hematology, University of Alberta, Edmonton, AB, Canada

  • Departments of Paediatrics and HPME, Mount Sinai Hospital and University of Toronto, Toronto, ON, Canada

  • Division of Gastroenterology, Hepatology and Nutrition, Hospital for Sick Children, Toronto, ON, Canada

  • Shaare Zedek Medical Center and the Hebrew University, Jerusalem, Israel

  • Department of Medicine & Pediatrics, Research Institute of McGill University Health Center, McGill University, Montreal, QC, Canada

  • Genetics and Genome Biology, Hospital for Sick Children Research Institute, Toronto, ON, Canada

  • Section of Hematology/Oncology, Department of Internal Medicine, University of Manitoba, Winnipeg, MB, Canada

  • Division of Gastroenterology, Queen's University, Kingston, ON, Canada

  • Centre for the Analysis of Genome Evolution & Function, University of Toronto, Toronto, ON, Canada

Locations

  • Canada

  • Israel

Companies

  • N/A

Study Components

Therapeutic Area

  • Gastroenterology (GU)

Disease

  • Crohn's disease

Biomarkers

  • Nucleotide-binding oligomerization domain-containing protein 2

  • Transcription factor Maf

Drug/Treatment

  • Kristalose Oral

  • Mecasermin rinfabate

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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