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Sa2017 : Blocking Peripheral Serotonin Synthesis by Telotristat Etiprate Reduces the Severity of Both Chemical- and Infection-Induced Intestinal Inflammation

Researchers

Presenter

  • Huaqing Wang

Principal Investigators

  • Joshua D. Terc

  • Ivana Sunjic

  • Brian Zambrowicz

  • Qi M. Yang

  • Waliul I. Khan

Medical Centers

  • Pathology and Molecular Medicine, Farncombe Family Digestive Health Research Institute, McMaster University, Hamilton, ON, Canada

Locations

  • Canada

Companies

  • Lexicon Pharmaceutic

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Inflammatory bowel disease

  • Irritable Bowel Syndrome

  • Ulcerative colitis

Biomarkers

  • Myeloperoxidase

  • Interleukin 1

  • Interleukin 17A

  • Interleukin 6

  • Serotonin

  • Tryptophan Hydroxylase 1

Drug/Treatment

  • Telotristat etiprate

  • tryptophan

  • Dex-HEMA

  • LX1606

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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