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Sa1774 : Cigarette Smoke Extract Decreases Regulatory T-Cells and Increases IFN-Gamma Secreting T-Cells in Peripheral Blood From Crohn's Disease Compared to Ulcerative Colitis Patients: Differential Smoking Effects on Two Types of Inflammatory Bowel Disease

Researchers

Presenter

  • Humberto Jijon

Principal Investigators

  • Suzanne Traves

  • Kim Ford

  • Ronald Chan

  • Paul L. Beck

  • Herman Barkema

  • Remo Panaccione

  • David Proud

  • Gilaad G. Kaplan

  • Subrata Ghosh

Medical Centers

  • The Alberta IBD Consortium, University of Calgary, Calgary, AB, Canada

  • Physiology & Pharmacology, University of Calgary, Calgary, AB, Canada

  • Department of Surgery, University of Calgary, Calgary, AB, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Inflammatory bowel disease

  • Ulcerative colitis

  • Crohn's disease

Biomarkers

  • Peripheral blood mononuclear cell

  • Cluster of Differentiation 25

  • Cluster of Differentiation 2AP

  • Cluster of Differentiation 4

  • Interferon-gamma

  • Interleukin 17A

  • Regulatory T cells

Drug/Treatment

  • lonomycin

  • IFN-lambda

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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