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Mo1987 : Do AMP-Activated Protein Kinase (AMPK) and Metformin Play a Role in the Small Intestine in Normal and Pathophysiological Conditions?

Researchers

Presenter

  • Elodie Harmel

Principal Investigators

  • Schohraya Spahis

  • Emilie Grenier

  • Ali Bendjoudi

  • Mounib Elchebly

  • Ehud Ziv

  • Martine Laville

  • Jean-Francois Beaulieu

  • Emile Levy

Medical Centers

  • Department of Gastroenterology, Sainte-Justine Hospital Research Center, Montreal, QC, Canada

  • Medicine, Rhone-Alpes Research Center, Hopital Edouard-Herriot, Lyon, France

  • Department of Oncology, McGill University, Montreal, QC, Canada

  • Department of Anatomy and Cellular Biology, Sherbrooke University, Sherbrooke, QC, Canada

Locations

  • France

  • Canada

  • Israel

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Type 2 diabetes mellitus

  • Dyslipidemia

  • Diabetes

  • AICAR transformylase/IMP cyclohydrolase deficiency

Biomarkers

  • Acetyl-CoA carboxylase

  • Mitogen-activated protein kinase 3

  • AMP-activated protein kinase

  • Nucleoside diphosphate kinase A

Drug/Treatment

  • Carnitine

  • Metformin Hydrochloride

  • AICAR

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim