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Mo1976 : Development of Novel Humanized Murine Models to Assess Mucosal Homeostasis: Human T Cells From Ipex (Immunodeficiency, Polyendocrinopathy, Enteropathy, X-Linked) Patients Transfer Clinical Phenotype to Immunodeficient Mice Expressing Human Class II

Researchers

Presenter

  • Jodie Ouahed

Principal Investigators

  • Katelyn McCann

  • Aleixo M. Muise

  • Scott Snapper

Medical Centers

  • Harvard Medical School, Boston, MA

  • Children's Hospital Boston, Boston, MA

  • University of Toronto, Toronto, ON, Canada

  • Children's Hospital Boston, Boston, ON, Canada

Locations

  • United States

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Autoimmune (AI)

Disease

  • Immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome

Biomarkers

  • Cluster of Differentiation 4

  • Forkhead Box P3

  • Major histocompatibility complex, class II, DR1

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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