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OR42-4 : X-Linked Acrogigantism (X-LAG): Novel Histopathological and Clinical Characterisation

Researchers

Presenter

  • Sian Jose

Principal Investigators

  • Claudia Ramirez

  • Moises Mercado

  • Anthony P. Goldstone

  • Michael Buchfelder

  • Christine Burren

  • Alper Gurlek

  • Pinaki Dutta

  • Catherine S. Choong

  • Tim D. Cheetham

  • Jacqueline Trouillas

  • Richard Caswell

  • Maria-Beatriz Lopes

  • Sian Ellard

  • Julian Sampson

  • Federico Roncaroli

  • Marta Korbonits

  • Sonal Kapur

  • Laura C. Hernandez-Ramirez

  • Francisca Caimari

  • Mary N. Dang

  • Plamena Gabrovska

  • Celia Rodd

  • Mary L. Vance

Medical Centers

  • PGIMER, Chandigarh, India

  • University of Exeter , Medical School, Exeter, United Kingdom

  • University of Erlangen-Nuernberg, Erlangen, Germany

  • University of Manchester, Manchester, United Kingdom

  • Hacettepe University School of Medicine, Ankara, Turkey

  • Princess Margaret Hospital for Children, Perth, Australia

  • Hospital de Especialidades Centro Medico Nacional S.XXI IMSS, Mexico

  • University of Virgina, Charlottesville, VA

  • Barts and the London School of Medicine, London, United Kingdom

  • Groupement Hospitalier Est, Bron, France

  • University Hospitals Bristol NHS Foundation Trust, Wells Somerset, United Kingdom

  • Department ofAnaeshesia, Royal Victoria Infirmary, Newcastle upon Tyne, United Kingdom

  • Cardiff University, Cardiff, United Kingdom

Locations

  • Canada

  • Germany

  • Turkey

  • United Kingdom

  • Australia

  • United States

  • Mexico

  • France

  • India

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

Disease

  • Acrogigantism syndrome

  • Hyperprolactinemia

  • Pituitary gigantism

  • Hypopituitarism

Biomarkers

  • Prolactin

  • Insulin-like growth factor 1

Drug/Treatment

  • Somatostatin

  • Pegvisomant

  • Dopamine hydrochloride

  • Mecasermin

Outcome

  • N/A


Study Design

  • double blind/blinded

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim