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FRI-523 : Effects of the Truncated Growth Hormone Receptor on GH and PRL Signaling

Researchers

Presenter

  • Cynthia Gates Goodyer

Principal Investigators

  • N/A

Medical Centers

  • Research Institute McGill University Health Center, Montreal, Quebec, Canada

  • Montreal University, Montreal, QC, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Musculoskeletal

Disease

  • Isolated short stature

Biomarkers

  • Mitogen-activated protein kinase

  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

  • Phosphorylated signal transducer and activator of transcription 5

  • Phosphorylated-extracellular signal regulated kinase

  • Prolactin

  • Prolactin receptor

  • DNA Damage Inducible Transcript 3

  • Extracellular signal-regulated kinase

  • Growth Hormone 1

  • Signal transducer and activator of transcription 5

  • PI3K/AKT

  • MAPK/ERK

Drug/Treatment

  • Human growth hormone

  • hGH

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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