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SAT-849 : IGF-I overexpression stimulates CCN5/WISP2 expression in pancreatic a-cells, which promotes cell proliferation and survival against streptozotocin

Researchers

Presenter

  • Xiao Wang

Principal Investigators

  • Bing Li

  • Coimbatore B Srikant

  • Jun-Li Liu

Medical Centers

  • Shanghai Jiaotong University, Shanghai, China

  • McGill University Health Centre, Montreal, QC, Canada

Locations

  • Canada

  • China

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Type 1 diabetes mellitus

  • Hereditary susceptibility to Wilms tumor 5

  • Retinoblastoma

  • Breast cancer

  • Diabetes

  • Solid malignancies

Biomarkers

  • Cyclin-dependent kinase 4

  • Epidermal growth factor

Drug/Treatment

  • Streptozotocin

  • Cysteine Hydrochloride

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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