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MON-96 : The FGFR4-G388R Polymorphism Signals Through Distinct STAT3 Modifications to Regulate Pituitary Corticotroph Tumors

Researchers

Presenter

  • Toru Tateno

Principal Investigators

  • Lei Zheng

  • Maw Maw Hliang

  • Katsuhiko Yoshimoto

  • Shozo Yamada

  • Sylvia L. Asa

  • Shereen Z Ezzat

Medical Centers

  • Toranomon Hospital, Tokyo, Japan

  • The University of Tokushima, Tokushima, Japan.

  • Ontario Cancer Institute, Toronto, ON, Canada

Locations

  • Canada

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Genetic Disorder

  • Oncology (ONC)

Disease

  • Pituitary adenomas

  • Pituitary adenoma 4, ACTH-secreting

Biomarkers

  • Fibroblast growth factor receptor

  • Fibroblast growth factor receptor 4

  • Growth Hormone 1

Drug/Treatment

  • hGH

  • Glucocorticoid

  • Dexamethasone

  • Dekpak 13 Day Taperpak

  • Arginine hydrochloride

  • L-Tyrosine

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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