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OR13-3 : Preterm Birth in Sheep Alters Adult Pancreatic Beta-Cell Mass and Expression of Key Genes Involved in Insulin Secretion and Hepatic Insulin Sensitivity

Researchers

Presenter

  • Jane M Alsweiler

Principal Investigators

  • Kristin L Connor

  • Mike Dragunow

  • Jane E Harding

  • Frank H Bloomfield

Medical Centers

  • Gravida: National Centre for Growth and Development, Auckland, New Zealand

  • University of Auckland, Auckland, New Zealand

  • Mount Sinai Hospital, Toronto, ON, Canada

Locations

  • Canada

  • New Zealand

Companies

  • N/A

Study Components

Therapeutic Area

  • Endocrine/metabolic Diseases (ME)

Disease

  • Prediabetes

  • Spontaneous preterm delivery

  • Hyperglycemia

Biomarkers

  • Peroxisome proliferator activated receptor

  • Insulin

Drug/Treatment

  • Glucocorticoid

  • Somatostatin

  • Intranasal glucagon

  • Dextrose Intravenous

Outcome

  • N/A


Study Design

  • randomized

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim