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Sa1996 : Crohn's Disease Associated NOD2 Variants Show Differential Activation of NFkB in Response to Autosignaling and Muramyl Dipeptide

Researchers

Presenter

  • Fraser Soares

Principal Investigators

  • Richard K. Russell

  • Stephen Girardin

  • Anne M. Griffiths

  • Dana Philpott

Medical Centers

  • Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada

  • Division of Pediatric Gastroenterology, Hepatology and Nutrition, Toronto Sick Kids Hospital, Toronto, ON, Canada

  • Department of Surgery, University of Toronto, Toronto, ON, Canada

  • Dept of Paediatric Gastroenterology, Yorkhill Hospital, Glasgow, United Kingdom

Locations

  • Canada

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Gastroenterology (GU)

Disease

  • Crohn's disease

Biomarkers

  • Nuclear factor kappa-light-chain-enhancer of activated B cells

  • Nucleotide-binding oligomerization domain-containing protein 2

Drug/Treatment

  • N/A

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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