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Mo1929 : Critical Role of Chromogranin-A on Macrophage Intrinsic Apoptotic Pathway in Colitis: Human and Animal studies

Researchers

Presenter

  • Mohammad F. Rabbi

Principal Investigators

  • Peris M. Munyaka

  • Azin Khafipour

  • Charles N. Bernstein

  • Jean-Eric Ghia

Medical Centers

  • Immunology & Internal Medicine section of Gastroenterology, University of Manitoba, Winnipeg, Manitoba, Canada

  • University of Mantioba, Winnipeg, MB, Canada

  • Childrens Hospital Research Institute of Manitoba/University of Manitoba, Winnipeg, MB, Canada

  • Immunology & Internal Medicine section of Gastroenterology, University of Manitoba, Winnipeg, Manitoba, Canada

Locations

  • Canada

Companies

  • N/A

Study Components

Therapeutic Area

  • Autoimmune (AI)

Disease

  • Ulcerative colitis

Biomarkers

  • C-C Motif Chemokine Ligand 2

  • Myeloperoxidase

  • BCL2 associated X, apoptosis regulator

  • BCL2 Binding Component 3

  • C-C Motif Chemokine Ligand 3

  • C-C Motif Chemokine Ligand 4

  • Chromogranin A

  • Interleukin 1

  • Interleukin 10

  • TNF Receptor Superfamily Member 1B

  • TNF superfamily member 10

  • Toll-like receptor 2

  • Tumor necrosis factor

Drug/Treatment

  • dextran sulfate sodium

  • Interleukin-10

Outcome

  • Unknown

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Interim

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