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8 : Guanylyl Cyclase A-Targeted Gene Therapy Ameliorates Disease Progression in Autosomal Recessive Polycystic Kidney Disease

Researchers

Presenter

  • Sara J. Holditch

Principal Investigators

  • Alessandro Cataliotti

  • Vicente Torres

  • Yasuhiro Ikeda

Medical Centers

  • Division of Nephrology and Hypertension, Mayo Clinic, Rochester, MN

  • Cardiorenal Research Laboratory, Mayo Clinic, Rochester, MN

  • Molecular Medicine, Mayo Graduate School, Mayo Clinic, Rochester, MN

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Nephrology

  • Genetic Disorder

Disease

  • Autosomal recessive polycystic kidney disease

  • Glomerulosclerosis

  • Renal disease

  • Acute renal failure

  • Hypertension

  • Albuminuria

Biomarkers

  • B-type natriuretic peptide

  • Creatinine

Drug/Treatment

  • DE-074

  • vasopressin Injection

  • Angiotensin II

  • Dermatan sulfate

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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