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934 : Carma1 Is Important for T-ALL CNS Infiltration and Survival in an Animal Model of T-ALL

Researchers

Presenter

  • Sreenivasa Rao Oruganti

Principal Investigators

  • Christina Halsey

  • Savannah Krebsbach

  • Francois Asperti-Boursin

  • Sumit Patel

  • Ksenia Matlawska-Wasowska

  • Stuart S. Winter

  • Judy Cannon

Medical Centers

  • Institute of Infection, Immunity and Inflammation, University of Glasgow, Glasgow, UK

  • Molecular Genetics & Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM

  • Molecular Genetics & Microbiology, University of New Mexico Health Sciences Center, Albuquerque, NM

  • Department of Pediatrics, Hematology/Oncology, University of New Mexico Health Sciences Center, Albuquerque, NM

Locations

  • United States

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Acute lymphoblastic leukemia

  • Squamous cell carcinoma of the head and neck

  • Mismatch repair deficiency

  • Lymphomas

  • Solid malignancies

  • T-cell acute lymphoblastic leukemia

  • B-cell acute lymphoblastic leukemia

Biomarkers

  • Neurogenic locus notch homolog protein 1

  • C-C Motif Chemokine Receptor 7

  • Cluster of Differentiation 25

Drug/Treatment

  • N/A

Outcome

  • N/A


Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final