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1436 : 12-HETrE, a Novel 12-LOX Oxylipin, Prevents Platelet Activation in a G?s-like Manner

Researchers

Presenter

  • Jennifer Yeung

Principal Investigators

  • Pilar Fernandez-Perez

  • Joanne Vesci

  • Theodore R Holman

  • Jin Ren

  • Michael Holinstat

Medical Centers

  • Cardeza Foundation for Hematologic Research and Department of Medicine, Thomas Jefferson University, Philadelphia, PA

  • Cardeza Foundation for Hematologic Research and Department of Medicine, Thomas Jefferson University, Philadelphia, PA

  • Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA

  • Cardeza Foundation for Hematologic Research and Department of Medicine, Thomas Jefferson University, Philadelphia, PA

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Venous thrombosis

Biomarkers

  • Cyclic adenosine monophosphate

  • Cyclic AMP-dependent protein kinase

  • Vasodilator Stimulated Phosphoprotein

Drug/Treatment

  • Prostacyclin

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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