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1434 : Identification of a Racially Dimorphic Variant in the Human Platelet PAR4 Thrombin Receptor Altering Platelet Function and Pharmacologic Inhibition

Researchers

Presenter

  • Leonard C. Edelstein

Principal Investigators

  • Lukas M Simon

  • Cory R Lindsay

  • Chad Shaw

  • Paul F Bray

  • Xiango Kong

  • Raul Teruel Montoya

  • Benjamin E Tourdot

  • Edward Chen

  • Lin Ma

  • Shaun R Coughlin

  • Marvin T. Nieman

  • Michael Holinstat

Medical Centers

  • Cardiovascular Research Institute, UCSF, San Francisco, CA

  • Cardeza Foundation for Hematologic Research and Department of Medicine, Thomas Jefferson University, Philadelphia, PA

  • Structural and Computational Biology and Molecular Biophysics, Baylor College of Medicine, Houston, TX

  • Dept. of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX.

  • Case Western Reserve University, Cleveland, OH

Locations

  • United States

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Peripheral artery disease

  • Coronary Artery Disease

  • Venous thrombosis

Biomarkers

  • N/A

Drug/Treatment

  • Phosphatidylinositol

  • LT 02

  • Vorapaxar

  • Evithrom

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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