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1542 : Discovery of a Novel, Potent, Selective and Injectable Small Molecule Inhibitor of Blood Coagulation Factor XIa, ONO-8610539: in Vitro and in Vivo Pharmacological Profiles

Researchers

Presenter

  • Masashi Gohda

Principal Investigators

  • Masaru Sakai

  • Kenji Tanaka

  • Taihei Nishiyama

  • Akira Imagawa

  • Kazuhito Kawabata

  • Tetsuya Hagio

  • Keizo Suzuki

  • Sho Koyama

  • Takehiro Ono

  • Ai Hashimoto

  • Hidekazu Matsuya

  • Yasushi Hirota

  • Takashi Kondo

Medical Centers

  • Ono Pharmaceutical, Osaka, Japan.

Locations

  • Japan

Companies

  • N/A

Study Components

Therapeutic Area

  • Cardiovascular (CVS)

  • Blood/haematological Diseases

  • Pulmonary/Respiratory Diseases

Disease

  • Deep vein thrombosis

  • Vasodilation dysfunction

  • Venous thrombosis

Biomarkers

  • Activated partial thromboplastin time

Drug/Treatment

  • ONO8610539

  • Isoflurane

  • Enoxaparin

  • Enoxaparin sodium

  • Ketamine Injection

Outcome

  • N/A

Study Design

  • N/A

Phase

  • NA

Study Id's

  • N/A

Sponsors

  • N/A

Result

  • Final

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