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1033 : Effect of metformin versus placebo on weight and metabolic factors in initial patients enrolled onto NCIC CTG MA.32, a multicenter adjuvant randomized controlled trial in early-stage breast cancer (BC).

Researchers

Presenter

  • Pamela Jean Goodwin

Principal Investigators

  • Karen A. Gelmon

  • Kathleen I. Pritchard

  • Timothy Joseph Whelan

  • Som Dave Mukherjee

  • Haji I. Chalchal

  • Conrad D. Oja

  • Katia Sonia Tonkin

  • Vanessa Bernstein

  • Bingshu E Chen

  • Dawn L. Hershman

  • Priya Rastogi

  • Ingrid A. Mayer

  • Timothy J. Hobday

  • Julie Lemieux

  • Alastair Mark Thompson

  • Vuk Stambolic

  • Lois E. Shepherd

  • Jennifer A. Ligibel

Medical Centers

  • National Surgical Adjuvant Breast and Bowel Project and University of Pittsburgh Cancer Institute, Pittsburgh, PA

  • Juravinski Cancer Centre at Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada

  • NCIC Clinical Trials Group, British Columbia Cancer Agency, University of British Columbia, Vancouver, BC, Canada

  • Allan Blair Cancer Ctr, Regina, SK, Canada

  • NCIC Clinical Trials Group, Cancer Research Institute, Queen's University, Kingston, ON, Canada

  • Lunenfeld-Tanenbaum Research Institute of Sinai Health System, University of Toronto, Toronto, Ontario, Canada

  • British Columbia Cancer Agency and the University of British Columbia, Vancouver, BC, Canada

  • Columbia University Medical Center, New York, NY

  • Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TNBritish Columbia Cancer Agency, Fraser Valley Center, Surrey, BC, CanadaUniversity of Alberta, Cross Cancer Institute, Edmonton, AB, Canada

  • Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA

  • National Cancer Research Institute Breast Clinical Studies Group, London, United Kingdom

  • University Health Network, Princess Margaret Cancer Centre, Toronto, ON, Canada

  • Mayo Clinic College of Medicine, Rochester, MN

  • University of Toronto, Toronto, ON, Canada

  • Centre de Recherche du CHU de Quebec, Unite de Recherche en sante des Populations Hopital du Saint-Sacrement, Quebec, QC, Canada

Locations

  • United States

  • Canada

  • United Kingdom

Companies

  • N/A

Study Components

Therapeutic Area

  • Oncology (ONC)

Disease

  • Breast cancer

Biomarkers

  • High sensitivity C-reactive protein

  • Insulin

Drug/Treatment

  • Metformin Hydrochloride

Outcome

  • N/A

Study Design

  • randomized

Phase

  • NA

Study Id's

  • NCT01101438

Sponsors

  • N/A

Result

  • N/A

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